Manuel Fernández or Fernandez may refer to:

• Manuel Fernández Ginés (born 1971), Spanish cyclist
• Manuel J. Fernandez (1925–1980), American pilot in Korean War
• Manuel José Fernández (born 1927), Argentine Olympic shooter
• Manuel Fernández Castrillón (1780s–1836), Mexican general
• Manuel Fernández Juncos (1846–1928), Spanish journalist and author
• Manuel Fernández Muñiz (born 1986), Spanish footballer
• Manuel Fernandez (businessman) (born 1946), American businessman
• Manuel Fernández Silvestre (1871–1921), Spanish general
• Manuel Fernandez (footballer) (1922–1971), French-Spanish football defender
• Manuel Fernández (rower), Argentine Olympic rower
• Manuel Fernández (Uruguayan footballer) (born 1989), Uruguayan footballer for Deportes Concepción
• Manuel Fernández (field hockey) (born 1948), Mexican former field hockey player
• Pahiño (Manuel Fernández Fernández, 1923–2012), Spanish footballer
• Manuel Montoya Fernández (1959–), Spanish handball manager
• Manuel Fernández Saro (born 1975), Spanish show jumping rider
• Manuel Fernández Caballero (1835–1906), Spanish composer
• Manuel Fernández Álvarez (1921-2010), Spanish historian and writer
• Manuel Fernández Mora (1932–2017), Spanish football player and manager