Bryan Smith may refer to:

• Bryan Smith, driver of a van that hit author Stephen King in 1999
  • Bryan Smith, a character in Stephen King's The Dark Tower based on the driver of the van that hit him
• Bryan Smith (American football) (born 1983), defensive end
• Bryan Smith (footballer) (born 1970), Scottish footballer (soccer) with Clydebank and Clyde
• Bryan Smith (motorcyclist), American motorcycle racer
• Bryan G. Smith, American chess grandmaster
• Bryan Smith, Canadian politician, Green Party candidate in Ontario 2003 election
• Bryan Smith, former member of Deep Banana Blackout
• Bryan Smith, presenter for the Australian television series Beyond Tomorrow
• Bryan Smyth (rugby league), Irish rugby league player