Luis Sánchez may refer to:

• Luis Sánchez (alpine skier) (born 1940), Spanish Olympic skier
• Luis Sánchez (baseball) (1953–2005), baseball player
• Luis Sánchez (basketball), Peruvian Olympic basketball player
• Luis Sánchez Betances (born 1947), Dominican attorney in Puerto Rico
• Luis Sánchez (Cuban footballer) (born 1952), Cuban footballer
• Luis Sánchez (Colombian footballer) (born 2000)
• Luis Sánchez Duque (born 1956), Spanish football manager
• Luis Sánchez Jiménez (born 1962), Mexican politician
• Luis Sánchez (Mexican footballer) (born 1988), Mexican footballer
• Luis Sánchez Morales (1867–1934), Puerto Rican politician
• Luis Sánchez Ossa (born 1988), Chilean politician
• Luis Sánchez de Tagle, 1st Marquis of Altamira (1642–1710), Spanish aristocrat

• Luis Alberto Sánchez (1900–1994), Peruvian lawyer
• Luis Ángel Sánchez (born 1993), Guatemalan racewalker
• Luis Augusto Sánchez (1917–1981), Colombian chess player
• Luis León Sánchez (born 1983), Spanish cyclist
• Luis Miguel Sánchez Cerro (1889–1933), Peruvian army officer
• Luis Rafael Sánchez (born 1936), Puerto Rican playwright