Baldini is a surname of Italian origin. Notable people with this surname include:

• Andrea Baldini (born 1985), Italian foil fencer
• Antonella Baldini (born 1966), Italian voice actress
• Baccio Baldini (1436–c. 1487), Italian engraver
• Christian Baldini (born 1978), Italian/Argentine/American composer and conductor
• Elvezia Michel-Baldini (1887–1963), Swiss painter
• Emmanuele Baldini (born 1971), Italian violinist and conductor
• Enrico Baldini (born 1996), Italian footballer
• Ercole Baldini (1933–2022), Italian road-racing bicyclist and Olympic medalist
• Francesco Baldini (born 1974), Italian footballer
• Franco Baldini (born 1960), Italian footballer and football technical director
• Giuseppe Baldini (1922–2009), Italian footballer and manager
• Jean-Pierre Baldini (born 1949), French sculptor
• Luca Baldini (born 1976), Italian swimmer
• Luisa Baldini (born ?), Australian-born UK journalist and presenter
• Marco Baldini (born 1959), Italian television personality and radio host
• Maria Teresa Baldini (born 1961), Italian politician, physician and basketball player
• Marino Baldini (born 1963), Croatian politician
• Nanni Baldini (born 1975), Italian voice actor
• Oreste Baldini (born 1962), Italian actor and voice actor
• Pietro Paolo Baldini (1614?–1684?), Italian painter of the Baroque era
• Raffaello Baldini (1924–2005), Italian writer and poet
• Renato Baldini (1921–1995), Italian film actor
• Sebastiano Baldini (1615–1685), Italian poet, librettist, and satirist
• Silvio Baldini (born 1958), Italian football manager
• Stefano Baldini (born 1971), Italian Olympic marathon runner
• Tiburzio Baldini (fl. early 17th century), Italian painter of the Baroque era
• Umberto Baldini (1921–2006), Italian art historian and restoration specialist
• Vittorio Baldini (died 1618), Italian printer and engraver