Hernán Medina Calderón (born August 29, 1937 in Yarumal, in the Antioquia Department, Colombia) is a retired Colombian road racing cyclist who won the Vuelta a Colombia in 1960 and the Vuelta a Guatemala in 1958. He also finished as runner up in the Vuelta a Colombia in 1959 and 1961. He competed in the individual road race and team time trial events at the 1960 Summer Olympics.