Alejandro Rodríguez may refer to:

• Alejandro Rodríguez (cyclist), Colombian road cyclist, competed in the 1998 Vuelta a Colombia
• Alejandro Rodríguez (footballer, born 1964), Spanish footballer
• Alejandro Rodríguez (footballer, born 1986), Uruguayan footballer
• Alejandro Rodríguez (footballer, born 1991), Spanish footballer
• Alejandro Rodriguez Jr. (born 1993), American soccer player
• Alejandro Rodríguez Luis (born 1957), Mexican politician
• Alejandro Rodríguez (politician) (born 1965), Argentine politician
• Alejandro Rodriguez (psychiatrist) (1918–2012), Venezuelan psychiatrist
• Alejandro Rodríguez (runner) (born 1989), Spanish runner and competitor at the 2014 IAAF World Relays – Men's 4 × 800 metres relay
• Alejandro Rodríguez (table tennis) (born 1978), Chilean table tennis player
• Alejandro Rodríguez de Valcárcel (1917–1976), Spanish politician and functionary
• Alejandro Rodríguez Velazco, (1852–1915), Cuban soldier and politician, mayor of Havana in 1900–1901