Luca Gelfi (21 June 1966 – 3 January 2009) was an Italian racing cyclist. A professional from 1988 to 1998, he won two stages of the 1990 Giro d'Italia and one of the 1997 Volta a Portugal. He finished second in the 1993 Milan–San Remo.

After retiring in 1998, he owned and operated a bike shop and directed Team Fratelli Giorgi, a prestigious junior cycling team.

Gelfi was diagnosed with clinical depression and died from suicide by hanging in 2009.