Jacopo Guarnieri (born 14 August 1987) is an Italian former road bicycle racer, who competed as a professional from 2009 to 2024 for five different teams.

During the early part of his professional career, Guarnieri took four victories including stage victories at the Tour de Pologne in 2009 and 2010. In the later part of his career, he was used as a lead-out man for sprinters such as Alexander Kristoff at Team Katusha, Arnaud Démare at Groupama–FDJ and Caleb Ewan at Lotto–Dstny.