Jacques Janse van Rensburg (born 6 September 1987) is a South African racing cyclist, who currently rides for amateur mountain biking team First Move. He is no relation to fellow South African professional cyclist Reinardt Janse van Rensburg.

During his road racing career, Janse van Rensburg rode in the 2014 Vuelta a España. He was named in the start list for the 2015 Tour de France. In the same year he won the South African National Road Race Championships. He was named in the start list for the 2017 Giro d'Italia.